Case Report Atypical presentation of Lupus Nephritis

Lupus Nephritis SLE PRESS SYNDROME

Abstract

Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can cause multi-organ involvement. Lupus nephritis is one of the most serious complications of SLE, affecting up to 60% of patients with SLE. While lupus nephritis is well known to clinicians, some pediatric cases may present with atypical symptoms, which can make it challenging to diagnose and manage. Hera we report a case a 12-year-old girl with an atypical presentation of lupus nephritis. She presented with fever, cough, vomiting, foamy urine, and swelling around her eyes. Lab results showed grade 3 renal impairment and positive ANA and anti-histone antibodies. A renal biopsy confirmed lupus nephritis. The patient was managed with hemodialysis and pulse steroids and cyclophosphamide, leading to significant improvement in her condition. We present a case report of a pediatric patient who presented with atypical symptoms of lupus nephritis, highlighting the diagnostic challenges and management strategies of this condition.CONCLUSION: In atypical Lupus nephritis the need for prompt diagnosis and appropriate management is essential to improve patient outcomes and prevent complications.