COVID-19 Vaccine Acquired Haemophilia:A case study and literature review
Keywords:
COVID-19vaccine, Acquired HaemophiliaAbstract
Afterviralinfectionsandcertainimmunizations,arangeofautoim-munediseaseshavebeenobserved.Acquiredantibodiesagainstco-agulationfactorVIIIcause acquired haemophiliaA(AHA),ararebleedingcondition.AHAislikelyunder-diagnosedandoftenunrecognizedduetolimiteddataaboutincidence,diagnosis,andmanagement.Wereportthecasestudyofa48-year-oldSaudimalepatientwithacquiredhaemophiliaafterCOVID-19vaccination.Hepresentedwithhematuriaandrightloinpain.HewasfoundtohaveprolongedaPTTnotcorrectedbymixingstudyandhisfactorIIIlevelwaslow.HewasmanagedbytheinsertionofarightureterstuntandrepeatedinfusionoffactorVII concentrate. Theetiologic,andpathologicbasisofacquiredhaemophiliashouldbeexploredmoreinthefuturetoclearlyelucidatethedisease.ExplorationofbetterandoptimalmedicaltherapeuticregimensisaneedfortimetotreatandpreventmorbidityinthepandemicofCOVID-19